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Allelic variants of IL1R1 gene associate with severe hand osteoarthritis

BACKGROUND: In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to severe OA of distal interphalangeal joints (DIP) in our...

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Detalles Bibliográficos
Autores principales: Näkki, Annu, Kouhia, Sanna T, Saarela, Janna, Harilainen, Arsi, Tallroth, Kaj, Videman, Tapio, Battié, Michele C, Kaprio, Jaakko, Peltonen, Leena, Kujala, Urho M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859817/
https://www.ncbi.nlm.nih.gov/pubmed/20353565
http://dx.doi.org/10.1186/1471-2350-11-50