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Allelic variants of IL1R1 gene associate with severe hand osteoarthritis
BACKGROUND: In search for genes predisposing to osteoarthritis (OA), several genome wide scans have provided evidence for linkage on 2q. In this study we targeted a 470 kb region on 2q11.2 presenting the locus with most evidence for linkage to severe OA of distal interphalangeal joints (DIP) in our...
Autores principales: | Näkki, Annu, Kouhia, Sanna T, Saarela, Janna, Harilainen, Arsi, Tallroth, Kaj, Videman, Tapio, Battié, Michele C, Kaprio, Jaakko, Peltonen, Leena, Kujala, Urho M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859817/ https://www.ncbi.nlm.nih.gov/pubmed/20353565 http://dx.doi.org/10.1186/1471-2350-11-50 |
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