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Protein Evolution via Amino Acid and Codon Elimination
BACKGROUND: Global residue-specific amino acid mutagenesis can provide important biological insight and generate proteins with altered properties, but at the risk of protein misfolding. Further, targeted libraries are usually restricted to a handful of amino acids because there is an exponential cor...
Autores principales: | Goltermann, Lise, Larsen, Marie Sofie Yoo, Banerjee, Rajat, Joerger, Andreas C., Ibba, Michael, Bentin, Thomas |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859931/ https://www.ncbi.nlm.nih.gov/pubmed/20436666 http://dx.doi.org/10.1371/journal.pone.0010104 |
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