Cargando…

Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway

BACKGROUND: PTEN (phosphatase and tensin homologue deleted on chromosome ten) is a tumor suppressor gene implicated in a wide variety of human cancers, including glioblastoma. PTEN is a major negative regulator of the PI3K/Akt signaling pathway. Most human gliomas show high levels of activated Akt,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dasari, Venkata Ramesh, Kaur, Kiranpreet, Velpula, Kiran Kumar, Gujrati, Meena, Fassett, Daniel, Klopfenstein, Jeffrey D., Dinh, Dzung H., Rao, Jasti S.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859936/ https://www.ncbi.nlm.nih.gov/pubmed/20436671 http://dx.doi.org/10.1371/journal.pone.0010350

Ejemplares similares

Cord Blood Stem Cell-Mediated Induction of Apoptosis in Glioma Downregulates X-Linked Inhibitor of Apoptosis Protein (XIAP)
por: Dasari, Venkata Ramesh, et al.
Publicado: (2010)

Downregulation of Focal Adhesion Kinase (FAK) by cord blood stem cells inhibits angiogenesis in glioblastoma
por: Dasari, Venkata Ramesh, et al.
Publicado: (2010)

Cord blood stem cells revert glioma stem cell EMT by down regulating transcriptional activation of Sox2 and Twist1
por: Velpula, Kiran Kumar, et al.
Publicado: (2011)

MMP-9, uPAR and Cathepsin B Silencing Downregulate Integrins in Human Glioma Xenograft Cells In Vitro and In Vivo in Nude Mice
por: Veeravalli, Krishna Kumar, et al.
Publicado: (2010)

Co-Depletion of Cathepsin B and uPAR Induces G0/G1 Arrest in Glioma via FOXO3a Mediated p27(Kip1) Upregulation
por: Gopinath, Sreelatha, et al.
Publicado: (2010)

MMP-2 siRNA Inhibits Radiation-Enhanced Invasiveness in Glioma Cells
por: Badiga, Aruna Venkata, et al.
Publicado: (2011)

Regulation of Glioblastoma Progression by Cord Blood Stem Cells Is Mediated by Downregulation of Cyclin D1
por: Velpula, Kiran Kumar, et al.
Publicado: (2011)

Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas
por: Malla, Ramarao, et al.
Publicado: (2010)

Cord Blood Stem Cells Inhibit Epidermal Growth Factor Receptor Translocation to Mitochondria in Glioblastoma
por: Dasari, Venkata Ramesh, et al.
Publicado: (2012)

Correction: Downregulation of uPAR and Cathepsin B Induces Apoptosis via Regulation of Bcl-2 and Bax and Inhibition of the PI3K/Akt Pathway in Gliomas
por: Malla, Ramarao, et al.
Publicado: (2014)

SPARC Overexpression Inhibits Cell Proliferation in Neuroblastoma and Is Partly Mediated by Tumor Suppressor Protein PTEN and AKT
por: Bhoopathi, Praveen, et al.
Publicado: (2012)

Role of MMP-2 in the Regulation of IL-6/Stat3 Survival Signaling via Interaction With α5β1 Integrin in glioma
por: Kesanakurti, Divya, et al.
Publicado: (2012)

Specific knockdown of uPA/uPAR attenuates invasion in glioblastoma cells and xenografts by inhibition of cleavage and trafficking of Notch -1 receptor
por: Raghu, Hari, et al.
Publicado: (2011)

Cathepsin B and uPAR Knockdown Inhibits Tumor-induced Angiogenesis by Modulating VEGF Expression in Glioma
por: Malla, Rama Rao, et al.
Publicado: (2011)

Metabolic remodeling precedes mitochondrial outer membrane permeabilization in human glioma xenograft cells
por: Ponnala, Shivani, et al.
Publicado: (2021)

Suppression of uPA and uPAR Attenuates Angiogenin Mediated Angiogenesis in Endothelial and Glioblastoma Cell Lines
por: Raghu, Hari, et al.
Publicado: (2010)

MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumors
por: Bhoopathi, Praveen, et al.
Publicado: (2011)

uPAR and cathepsin B-mediated compartmentalization of JNK regulates the migration of glioma-initiating cells
por: Alapati, Kiranmai, et al.
Publicado: (2014)

Suppression of uPAR Retards Radiation-Induced Invasion and Migration Mediated by Integrin β1/FAK Signaling in Medulloblastoma
por: Nalla, Arun Kumar, et al.
Publicado: (2010)

Epigenetic Regulation of miRNA-211 by MMP-9 Governs Glioma Cell Apoptosis, Chemosensitivity and Radiosensitivity
por: Asuthkar, Swapna, et al.
Publicado: (2012)

Temporal Regulation of Apoptotic and Anti-apoptotic Molecules After Middle Cerebral Artery Occlusion Followed by Reperfusion
por: Chelluboina, Bharath, et al.
Publicado: (2013)

uPAR and cathepsin B knockdown inhibits radiation-induced PKC integrated integrin signaling to the cytoskeleton of glioma-initiating cells
por: ALAPATI, KIRANMAI, et al.
Publicado: (2012)

α3β1 integrin promotes radiation-induced migration of meningioma cells
por: Gogineni, Venkateswara Rao, et al.
Publicado: (2021)

Regulation of DNA Repair Mechanism in Human Glioma Xenograft Cells both In Vitro and In Vivo in Nude Mice
por: Ponnala, Shivani, et al.
Publicado: (2011)

Retraction: Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway
Publicado: (2020)

MMP-2 suppression abrogates irradiation-induced microtubule formation in endothelial cells by inhibiting αvβ3-mediated SDF-1/CXCR4 signaling
por: MADDIRELA, DILIP RAJASEKHAR, et al.
Publicado: (2013)

Involvement of nitric oxide synthase in matrix metalloproteinase-9- and/or urokinase plasminogen activator receptor-mediated glioma cell migration
por: Zhuang, Thompson, et al.
Publicado: (2013)

Lactobacillus plantarum induces apoptosis in oral cancer KB cells through upregulation of PTEN and downregulation of MAPK signalling pathways
por: Asoudeh-Fard, Abbas, et al.
Publicado: (2017)

Triptolide Induces Glioma Cell Autophagy and Apoptosis via Upregulating the ROS/JNK and Downregulating the Akt/mTOR Signaling Pathways
por: Liu, Xihong, et al.
Publicado: (2019)

Estrogen receptor β represses Akt signaling in breast cancer cells via downregulation of HER2/HER3 and upregulation of PTEN: implications for tamoxifen sensitivity
por: Lindberg, Karolina, et al.
Publicado: (2011)

Downregulation of the Cd38-Cyclic ADP-Ribose Signaling in Cardiomyocytes by Intermittent Hypoxia via Pten Upregulation
por: Takasawa, Shin, et al.
Publicado: (2022)

Long non-coding RNA CASC2 upregulates PTEN to suppress pancreatic carcinoma cell metastasis by downregulating miR-21
por: Zhang, Hui, et al.
Publicado: (2019)

Downregulation of miR-221/222 by a microRNA sponge promotes apoptosis in oral squamous cell carcinoma cells through upregulation of PTEN
por: Zhou, Lijie, et al.
Publicado: (2016)

Downregulation of hsa_circ_0001836 Induces Pyroptosis Cell Death in Glioma Cells via Epigenetically Upregulating NLRP1
por: Liu, Yong, et al.
Publicado: (2021)

Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma
por: Niu, Hai-Tao, et al.
Publicado: (2021)

Downregulation of miR-99b-5p and Upregulation of Nuclear mTOR Cooperatively Promotes the Tumor Aggressiveness and Drug Resistance in African American Prostate Cancer
por: Gujrati, Himali, et al.
Publicado: (2022)

Circadian Period 2 (Per2) downregulate inhibitor of differentiation 3 (Id3) expression via PTEN/AKT/Smad5 axis to inhibits glioma cell proliferation
por: Zhang, Yifan, et al.
Publicado: (2022)

Compound 331 selectively induces glioma cell death by upregulating miR-494 and downregulating CDC20
por: Zhang, Lei, et al.
Publicado: (2015)

MMP-9 and uPAR regulated glioma cell migration
por: Veeravalli, Krishna Kumar, et al.
Publicado: (2012)

Galectin-1 activates carbonic anhydrase IX and modulates glioma metabolism
por: Guda, Maheedhara R., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rs98jcufr43m81i29ppbai0me1