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Prions of Ruminants Show Distinct Splenotropisms in an Ovine Transgenic Mouse Model
BACKGROUND: Transmissible agents involved in prion diseases differ in their capacities to target different regions of the central nervous system and lymphoid tissues, which are also host-dependent. METHODOLOGY/PRINCIPAL FINDINGS: Protease-resistant prion protein (PrP(res)) was analysed by Western bl...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859945/ https://www.ncbi.nlm.nih.gov/pubmed/20436680 http://dx.doi.org/10.1371/journal.pone.0010310 |