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The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores

The metazoan nuclear pore complex (NPC) disassembles during mitosis, and many of its constituents distribute onto spindles and kinetochores, including the Nup107-160 sub-complex1,2. We have found that Nup107-160 interacts with the γ-tubulin ring complex (γ-TuRC), an essential and conserved microtubu...

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Detalles Bibliográficos
Autores principales: Mishra, Ram Kumar, Chakraborty, Papia, Arnaoutov, Alexei, Fontoura, Beatriz M.A., Dasso, Mary
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2859955/
https://www.ncbi.nlm.nih.gov/pubmed/20081840
http://dx.doi.org/10.1038/ncb2016