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Iminodiacetic-phosphoramidates as metabolic prototypes for diversifying nucleic acid polymerization in vivo
Previous studies in our laboratory proved that certain functional groups are able to mimic the pyrophosphate moiety and act as leaving groups in the enzymatic polymerization of deoxyribonucleic acids by HIV-1 reverse transcriptase. When the potential leaving group possesses two carboxylic acid moiet...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860114/ https://www.ncbi.nlm.nih.gov/pubmed/20097909 http://dx.doi.org/10.1093/nar/gkp1246 |