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Structural Elucidation of Cisoid and Transoid Cyclization Pathways of a Sesquiterpene Synthase Using 2-Fluorofarnesyl Diphosphates

[Image: see text] Sesquiterpene skeletal complexity in nature originates from the enzyme-catalyzed ionization of (trans,trans)-farnesyl diphosphate (FPP) (1a) and subsequent cyclization along either 2,3-transoid or 2,3-cisoid farnesyl cation pathways. Tobacco 5-epi-aristolochene synthase (TEAS), a t...

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Detalles Bibliográficos
Autores principales:	Noel, Joseph P., Dellas, Nikki, Faraldos, Juan A., Zhao, Marylin, Hess, B. Andes, Smentek, Lidia, Coates, Robert M., O’Maille, Paul E.
Formato:	Texto
Lenguaje:	English
Publicado:	American Chemical Society 2010
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860371/ https://www.ncbi.nlm.nih.gov/pubmed/20175559 http://dx.doi.org/10.1021/cb900295g

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