Genetic Immunization with CDR3-Based Fusion Vaccine Confers Protection and Long-Term Tumor-Free Survival in a Mouse Model of Lymphoma

Therapeutic vaccination against idiotype is a promising strategy for immunotherapy of B-cell malignancies. We have previously shown that CDR3-based DNA immunization can induce immune response against lymphoma and explored this strategy to provide protection in a murine B-cell lymphoma model. Here we...

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Detalles Bibliográficos
Autores principales: Iurescia, Sandra, Fioretti, Daniela, Pierimarchi, Pasquale, Signori, Emanuela, Zonfrillo, Manuela, Tonon, Giancarlo, Fazio, Vito M., Rinaldi, Monica
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860581/
https://www.ncbi.nlm.nih.gov/pubmed/20445751
http://dx.doi.org/10.1155/2010/316069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860581/
https://www.ncbi.nlm.nih.gov/pubmed/20445751
http://dx.doi.org/10.1155/2010/316069

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