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Stable ATP binding mediated by a partial NBD dimer of the CFTR chloride channel

Cystic fibrosis transmembrane conductance regulator (CFTR), a member of the adenosine triphosphate (ATP) binding cassette (ABC) superfamily, is an ATP-gated chloride channel. Like other ABC proteins, CFTR encompasses two nucleotide binding domains (NBDs), NBD1 and NBD2, each accommodating an ATP bin...

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Detalles Bibliográficos
Autores principales:	Tsai, Ming-Feng, Li, Min, Hwang, Tzyh-Chang
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860585/ https://www.ncbi.nlm.nih.gov/pubmed/20421370 http://dx.doi.org/10.1085/jgp.201010399

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