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Role of phosphoinositides in STIM1 dynamics and store-operated calcium entry

Ca(2+) entry through store-operated Ca(2+) channels involves the interaction at ER–PM (endoplasmic reticulum–plasma membrane) junctions of STIM (stromal interaction molecule) and Orai. STIM proteins are sensors of the luminal ER Ca(2+) concentration and, following depletion of ER Ca(2+), they oligom...

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Detalles Bibliográficos
Autores principales: Walsh, Ciara M., Chvanov, Michael, Haynes, Lee P., Petersen, Ole H., Tepikin, Alexei V., Burgoyne, Robert D.
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860680/
https://www.ncbi.nlm.nih.gov/pubmed/19843011
http://dx.doi.org/10.1042/BJ20090884