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Vitamin D and Human Skeletal Muscle

Vitamin D deficiency is an increasingly described phenomenon worldwide, with well-known impacts on calcium metabolism and bone health. Vitamin D has also been associated with chronic health problems such as bowel and colonic cancer, arthritis, diabetes and cardiovascular disease. In recent decades,...

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Detalles Bibliográficos
Autor principal: Hamilton, B
Formato: Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860762/
https://www.ncbi.nlm.nih.gov/pubmed/19807897
http://dx.doi.org/10.1111/j.1600-0838.2009.01016.x
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author Hamilton, B
author_facet Hamilton, B
author_sort Hamilton, B
collection PubMed
description Vitamin D deficiency is an increasingly described phenomenon worldwide, with well-known impacts on calcium metabolism and bone health. Vitamin D has also been associated with chronic health problems such as bowel and colonic cancer, arthritis, diabetes and cardiovascular disease. In recent decades, there has been increased awareness of the impact of vitamin D on muscle morphology and function, but this is not well recognized in the Sports Medicine literature. In the early 20th century, athletes and coaches felt that ultraviolet rays had a positive impact on athletic performance, and increasingly, evidence is accumulating to support this view. Both cross-sectional and longitudinal studies allude to a functional role for vitamin D in muscle and more recently the discovery of the vitamin D receptor in muscle tissue provides a mechanistic understanding of the function of vitamin D within muscle. The identification of broad genomic and non-genomic roles for vitamin D within skeletal muscle has highlighted the potential impact vitamin D deficiency may have on both underperformance and the risk of injury in athletes. This review describes the current understanding of the role vitamin D plays within skeletal muscle tissue.
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spelling pubmed-28607622010-05-07 Vitamin D and Human Skeletal Muscle Hamilton, B Scand J Med Sci Sports Review Articles Vitamin D deficiency is an increasingly described phenomenon worldwide, with well-known impacts on calcium metabolism and bone health. Vitamin D has also been associated with chronic health problems such as bowel and colonic cancer, arthritis, diabetes and cardiovascular disease. In recent decades, there has been increased awareness of the impact of vitamin D on muscle morphology and function, but this is not well recognized in the Sports Medicine literature. In the early 20th century, athletes and coaches felt that ultraviolet rays had a positive impact on athletic performance, and increasingly, evidence is accumulating to support this view. Both cross-sectional and longitudinal studies allude to a functional role for vitamin D in muscle and more recently the discovery of the vitamin D receptor in muscle tissue provides a mechanistic understanding of the function of vitamin D within muscle. The identification of broad genomic and non-genomic roles for vitamin D within skeletal muscle has highlighted the potential impact vitamin D deficiency may have on both underperformance and the risk of injury in athletes. This review describes the current understanding of the role vitamin D plays within skeletal muscle tissue. Blackwell Publishing Ltd 2010-04 /pmc/articles/PMC2860762/ /pubmed/19807897 http://dx.doi.org/10.1111/j.1600-0838.2009.01016.x Text en © 2010 John Wiley & Sons A/S http://creativecommons.org/licenses/by/2.5/ Re-use of this article is permitted in accordance with the Creative Commons Deed, Attribution 2.5, which does not permit commercial exploitation.
spellingShingle Review Articles
Hamilton, B
Vitamin D and Human Skeletal Muscle
title Vitamin D and Human Skeletal Muscle
title_full Vitamin D and Human Skeletal Muscle
title_fullStr Vitamin D and Human Skeletal Muscle
title_full_unstemmed Vitamin D and Human Skeletal Muscle
title_short Vitamin D and Human Skeletal Muscle
title_sort vitamin d and human skeletal muscle
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860762/
https://www.ncbi.nlm.nih.gov/pubmed/19807897
http://dx.doi.org/10.1111/j.1600-0838.2009.01016.x
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