Cargando…

Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes

SPP (signal peptide peptidase) is an aspartyl intramembrane cleaving protease, which processes a subset of signal peptides, and is linked to the quality control of ER (endoplasmic reticulum) membrane proteins. We analysed SPP interactions with signal peptides and other membrane proteins by co-immuno...

Descripción completa

Detalles Bibliográficos
Autores principales: Schrul, Bianca, Kapp, Katja, Sinning, Irmgard, Dobberstein, Bernhard
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860808/
https://www.ncbi.nlm.nih.gov/pubmed/20196774
http://dx.doi.org/10.1042/BJ20091005