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Signal peptide peptidase (SPP) assembles with substrates and misfolded membrane proteins into distinct oligomeric complexes
SPP (signal peptide peptidase) is an aspartyl intramembrane cleaving protease, which processes a subset of signal peptides, and is linked to the quality control of ER (endoplasmic reticulum) membrane proteins. We analysed SPP interactions with signal peptides and other membrane proteins by co-immuno...
Autores principales: | Schrul, Bianca, Kapp, Katja, Sinning, Irmgard, Dobberstein, Bernhard |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2860808/ https://www.ncbi.nlm.nih.gov/pubmed/20196774 http://dx.doi.org/10.1042/BJ20091005 |
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