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Feasibility and Diagnostic Utility of Antigen-Specific Interferon-γ Responses for Rapid Immunodiagnosis of Tuberculosis Using Induced Sputum

BACKGROUND: The diagnosis of smear-negative or sputum-scarce tuberculosis (TB) is problematic as culture takes several weeks and representative biological samples are difficult to obtain. RD-1 antigen-specific interferon-γ release assays (IGRAs) are sensitive and specific blood-based tests for the d...

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Detalles Bibliográficos
Autores principales:	Cashmore, Tamaryn J., Peter, Jonathan G., van Zyl-Smit, Richard N., Semple, Patricia L., Maredza, Alice, Meldau, Richard, Zumla, Alimuddin, Nurse, Barbara, Dheda, Keertan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861000/ https://www.ncbi.nlm.nih.gov/pubmed/20442850 http://dx.doi.org/10.1371/journal.pone.0010389

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