Expression of the Rap1 Guanine Nucleotide Exchange Factor, MR-GEF, Is Altered in Individuals with Bipolar Disorder

In the rodent forebrain GABAergic neurons are generated from progenitor cells that express the transcription factors Dlx1 and Dlx2. The Rap-1 guanine nucleotide exchange factor, MR-GEF, is turned on by many of these developing GABAergic neurons. Expression of both Dlx1/2 and MR-GEF is retained in bo...

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Detalles Bibliográficos
Autores principales: Bithell, Angela, Hsu, Tony, Kandanearatchi, Apsara, Landau, Sabine, Everall, Ian P., Tsuang, Ming T., Chana, Gursharan, Williams, Brenda P.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861006/
https://www.ncbi.nlm.nih.gov/pubmed/20436929
http://dx.doi.org/10.1371/journal.pone.0010392

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