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Abdominal irradiation modulates 5-Fluorouracil pharmacokinetics

BACKGROUND: Concurrent chemoradiation with 5-fluorouracil (5-FU) is widely accepted for treatment of abdominal malignancy. Nonetheless, the interactions between radiation and 5-FU remain unclear. We evaluated the influence of abdominal irradiation on the pharmacokinetics of 5-FU in rats. METHODS: Th...

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Detalles Bibliográficos
Autores principales:	Hsieh, Chen-Hsi, Hsieh, Yen-Ju, Liu, Chia-Yuan, Tai, Hung-Chi, Huang, Yu-Chuen, Shueng, Pei-Wei, Wu, Le-Jung, Wang, Li-Ying, Tsai, Tung-Hu, Chen, Yu-Jen
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861020/ https://www.ncbi.nlm.nih.gov/pubmed/20338060 http://dx.doi.org/10.1186/1479-5876-8-29

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