Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(δ/δ )mouse model of amyotrophic lateral sclerosis

BACKGROUND: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo. Deletion of the hypoxia response element of the promoter region of the gene encoding VEGF in mice causes a...

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Detalles Bibliográficos
Autores principales: Brockington, Alice, Heath, Paul R, Holden, Hazel, Kasher, Paul, Bender, Florian LP, Claes, Filip, Lambrechts, Diether, Sendtner, Michael, Carmeliet, Peter, Shaw, Pamela J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861063/
https://www.ncbi.nlm.nih.gov/pubmed/20346106
http://dx.doi.org/10.1186/1471-2164-11-203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861063/
https://www.ncbi.nlm.nih.gov/pubmed/20346106
http://dx.doi.org/10.1186/1471-2164-11-203

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