Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGF(δ/δ )mouse model of amyotrophic lateral sclerosis

BACKGROUND: Vascular endothelial growth factor (VEGF) is an endothelial cell mitogen that stimulates vasculogenesis. It has also been shown to act as a neurotrophic factor in vitro and in vivo. Deletion of the hypoxia response element of the promoter region of the gene encoding VEGF in mice causes a...

Descripción completa

Detalles Bibliográficos
Autores principales: Brockington, Alice, Heath, Paul R, Holden, Hazel, Kasher, Paul, Bender, Florian LP, Claes, Filip, Lambrechts, Diether, Sendtner, Michael, Carmeliet, Peter, Shaw, Pamela J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861063/
https://www.ncbi.nlm.nih.gov/pubmed/20346106
http://dx.doi.org/10.1186/1471-2164-11-203

Ejemplares similares

Ejemplares similares