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Cleaved high molecular weight kininogen and its domain 5 inhibit migration and invasion of human prostate cancer cells via the epidermal growth factor receptor pathway

Up-regulation and activation of epidermal growth factor receptor and/or urokinase-type plasminogen activator receptor in a variety of cancers have been shown to be associated with poor prognosis. High molecular weight kininogen can be hydrolyzed by plasma kallikrein to bradykinin and HKa. HKa and it...

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Detalles Bibliográficos
Autores principales: Liu, Yuchuan, Pixley, Robin, Fusaro, Mario, Godoy, Gustavo, Kim, Erin, Bromberg, Michael E., Colman, Robert W.
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861141/
https://www.ncbi.nlm.nih.gov/pubmed/19483730
http://dx.doi.org/10.1038/onc.2009.132