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The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes

Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study Design. IRB approval was obtained for this retrospective analysis and chart review was performed. Results. From 268 women with ea...

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Autores principales: Gray, Heidi J., Seifert, Erin, Sal y Rosas, Victor G., Nicandri, Katrina F., Koh, Wui-Jin, Goff, Barbara A.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861195/
https://www.ncbi.nlm.nih.gov/pubmed/20454444
http://dx.doi.org/10.1155/2010/743794
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author Gray, Heidi J.
Seifert, Erin
Sal y Rosas, Victor G.
Nicandri, Katrina F.
Koh, Wui-Jin
Goff, Barbara A.
author_facet Gray, Heidi J.
Seifert, Erin
Sal y Rosas, Victor G.
Nicandri, Katrina F.
Koh, Wui-Jin
Goff, Barbara A.
author_sort Gray, Heidi J.
collection PubMed
description Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study Design. IRB approval was obtained for this retrospective analysis and chart review was performed. Results. From 268 women with early-stage (IA2 to IIA) cervical cancer, 19 (7%) had an abandoned hysterectomy for finding grossly positive lymph nodes (84%) or pelvic spread of tumor (16%). No clinical characteristics clearly identified women preoperatively at risk of having an abandoned hysterectomy. In the abandoned group, 26% suffered major morbidities, compared to 34% in the completed group (OR 0.69, [CI 0.16–2.57], P = .789). Thirty-seven percent recurred in the abandoned group, compared to 18% in the completed group (P = .168). Overall survival in the abandoned group was 73% versus 80% in the completed group (P = .772). Conclusion. The practice of abandoning a planned radical hysterectomy for unexpected metastatic disease may not worsen the outcome.
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spelling pubmed-28611952010-05-07 The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes Gray, Heidi J. Seifert, Erin Sal y Rosas, Victor G. Nicandri, Katrina F. Koh, Wui-Jin Goff, Barbara A. Obstet Gynecol Int Clinical Study Objective. Cervical cancer patients who had an abandoned radical hysterectomy were evaluated for preoperative clinical predictors, complication rates, and outcomes. Study Design. IRB approval was obtained for this retrospective analysis and chart review was performed. Results. From 268 women with early-stage (IA2 to IIA) cervical cancer, 19 (7%) had an abandoned hysterectomy for finding grossly positive lymph nodes (84%) or pelvic spread of tumor (16%). No clinical characteristics clearly identified women preoperatively at risk of having an abandoned hysterectomy. In the abandoned group, 26% suffered major morbidities, compared to 34% in the completed group (OR 0.69, [CI 0.16–2.57], P = .789). Thirty-seven percent recurred in the abandoned group, compared to 18% in the completed group (P = .168). Overall survival in the abandoned group was 73% versus 80% in the completed group (P = .772). Conclusion. The practice of abandoning a planned radical hysterectomy for unexpected metastatic disease may not worsen the outcome. Hindawi Publishing Corporation 2010 2010-04-28 /pmc/articles/PMC2861195/ /pubmed/20454444 http://dx.doi.org/10.1155/2010/743794 Text en Copyright © 2010 Heidi J. Gray et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Study
Gray, Heidi J.
Seifert, Erin
Sal y Rosas, Victor G.
Nicandri, Katrina F.
Koh, Wui-Jin
Goff, Barbara A.
The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title_full The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title_fullStr The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title_full_unstemmed The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title_short The Abandoned Radical Hysterectomy for Cervical Cancer: Clinical Predictors and Outcomes
title_sort abandoned radical hysterectomy for cervical cancer: clinical predictors and outcomes
topic Clinical Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861195/
https://www.ncbi.nlm.nih.gov/pubmed/20454444
http://dx.doi.org/10.1155/2010/743794
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