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Evidence for STAT4 as a Common Autoimmune Gene: rs7574865 Is Associated with Colonic Crohn's Disease and Early Disease Onset

BACKGROUND: Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STAT4 variants on the susceptibil...

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Detalles Bibliográficos
Autores principales: Glas, Jürgen, Seiderer, Julia, Nagy, Melinda, Fries, Christoph, Beigel, Florian, Weidinger, Maria, Pfennig, Simone, Klein, Wolfram, Epplen, Jörg T., Lohse, Peter, Folwaczny, Matthias, Göke, Burkhard, Ochsenkühn, Thomas, Diegelmann, Julia, Müller-Myhsok, Bertram, Roeske, Darina, Brand, Stephan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861592/
https://www.ncbi.nlm.nih.gov/pubmed/20454450
http://dx.doi.org/10.1371/journal.pone.0010373