Effects of Long-Term Pioglitazone Treatment on Peripheral and Central Markers of Aging

BACKGROUND: Thiazolidinediones (TZDs) activate peroxisome proliferator-activated receptor gamma (PPARγ) and are used clinically to help restore peripheral insulin sensitivity in Type 2 diabetes (T2DM). Interestingly, long-term treatment of mouse models of Alzheimer's disease (AD) with TZDs also...

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Detalles Bibliográficos
Autores principales: Blalock, Eric M., Phelps, Jeremiah T., Pancani, Tristano, Searcy, James L., Anderson, Katie L., Gant, John C., Popovic, Jelena, Avdiushko, Margarita G., Cohen, Don A., Chen, Kuey-Chu, Porter, Nada M., Thibault, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861595/
https://www.ncbi.nlm.nih.gov/pubmed/20454453
http://dx.doi.org/10.1371/journal.pone.0010405

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