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HSP90 Protein Stabilizes Unloaded Argonaute Complexes and Microscopic P-bodies in Human Cells

Key components of the miRNA-mediated gene regulation pathway are localized in cytoplasmic processing bodies (P-bodies). Mounting evidence suggests that the presence of microscopic P-bodies are not always required for miRNA-mediated gene regulation. Here we have shown that geldanamycin, a well-charac...

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Detalles Bibliográficos
Autores principales: Johnston, Michael, Geoffroy, Marie-Claude, Sobala, Andrew, Hay, Ron, Hutvagner, Gyorgy
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861606/
https://www.ncbi.nlm.nih.gov/pubmed/20237157
http://dx.doi.org/10.1091/mbc.E09-10-0885

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