Posttranslational Modification of Human Glyoxalase 1 Indicates Redox-Dependent Regulation

BACKGROUND: Glyoxalase 1 (Glo1) and glyoxalase 2 (Glo2) are ubiquitously expressed cytosolic enzymes that catalyze the conversion of toxic α-oxo-aldehydes into the corresponding α-hydroxy acids using L-glutathione (GSH) as a cofactor. Human Glo1 exists in various isoforms; however, the nature of its...

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Detalles Bibliográficos
Autores principales: Birkenmeier, Gerd, Stegemann, Christin, Hoffmann, Ralf, Günther, Robert, Huse, Klaus, Birkemeyer, Claudia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861629/
https://www.ncbi.nlm.nih.gov/pubmed/20454679
http://dx.doi.org/10.1371/journal.pone.0010399

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