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Spatial Distribution of Factor Xa, Thrombin, and Fibrin(ogen) on Thrombi at Venous Shear
BACKGROUND: The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor...
Autores principales: | Berny, Michelle A., Munnix, Imke C. A., Auger, Jocelyn M., Schols, Saskia E. M., Cosemans, Judith M. E. M., Panizzi, Peter, Bock, Paul E., Watson, Steve P., McCarty, Owen J. T., Heemskerk, Johan W. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861630/ https://www.ncbi.nlm.nih.gov/pubmed/20454680 http://dx.doi.org/10.1371/journal.pone.0010415 |
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