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Investigation of PARP-1, PARP-2, and PARG interactomes by affinity-purification mass spectrometry
BACKGROUND: Poly(ADP-ribose) polymerases (PARPs) catalyze the formation of poly(ADP-ribose) (pADPr), a post-translational modification involved in several important biological processes, namely surveillance of genome integrity, cell cycle progression, initiation of the DNA damage response, apoptosis...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861645/ https://www.ncbi.nlm.nih.gov/pubmed/20388209 http://dx.doi.org/10.1186/1477-5956-8-22 |