High frequency of Machado-Joseph disease identified in Southeastern Chinese kindreds with spinocerebellar ataxia

BACKGROUND: Machado-Joseph disease (MJD), caused by a CAG repeat expansion located in exon10 of the ATXN3 gene, is now regarded as one of the most common spinocerebellar ataxia (SCA) in the world. The relative frequency of MJD among SCA has previously been estimated at about 50% in the Chinese popul...

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Detalles Bibliográficos
Autores principales: Gan, Shi-Rui, Shi, Sheng-Sheng, Wu, Jian-Jun, Wang, Ning, Zhao, Gui-Xian, Weng, Sheng-Tong, Murong, Shen-Xing, Lu, Chuan-Zhen, Wu, Zhi-Ying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861663/
https://www.ncbi.nlm.nih.gov/pubmed/20334689
http://dx.doi.org/10.1186/1471-2350-11-47

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861663/
https://www.ncbi.nlm.nih.gov/pubmed/20334689
http://dx.doi.org/10.1186/1471-2350-11-47

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