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Asymmetric Switching in a Homodimeric ABC Transporter: A Simulation Study
ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nu...
Autores principales: | Aittoniemi, Jussi, de Wet, Heidi, Ashcroft, Frances M., Sansom, Mark S. P. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861673/ https://www.ncbi.nlm.nih.gov/pubmed/20454684 http://dx.doi.org/10.1371/journal.pcbi.1000762 |
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