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Genome-Wide Association Study of Lp-PLA(2) Activity and Mass in the Framingham Heart Study

Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) is an emerging risk factor and therapeutic target for cardiovascular disease. The activity and mass of this enzyme are heritable traits, but major genetic determinants have not been explored in a systematic, genome-wide fashion. We carried out a...

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Detalles Bibliográficos
Autores principales:	Suchindran, Sunil, Rivedal, David, Guyton, John R., Milledge, Tom, Gao, Xiaoyi, Benjamin, Ashlee, Rowell, Jennifer, Ginsburg, Geoffrey S., McCarthy, Jeanette J.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861686/ https://www.ncbi.nlm.nih.gov/pubmed/20442857 http://dx.doi.org/10.1371/journal.pgen.1000928

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