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Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies

Homoploid hybrid speciation is the formation of a new hybrid species without change in chromosome number. So far, there has been a lack of direct molecular evidence for hybridization generating novel traits directly involved in animal speciation. Heliconius butterflies exhibit bright aposematic colo...

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Autores principales: Salazar, Camilo, Baxter, Simon W., Pardo-Diaz, Carolina, Wu, Grace, Surridge, Alison, Linares, Mauricio, Bermingham, Eldredge, Jiggins, Chris D.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861694/
https://www.ncbi.nlm.nih.gov/pubmed/20442862
http://dx.doi.org/10.1371/journal.pgen.1000930
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author Salazar, Camilo
Baxter, Simon W.
Pardo-Diaz, Carolina
Wu, Grace
Surridge, Alison
Linares, Mauricio
Bermingham, Eldredge
Jiggins, Chris D.
author_facet Salazar, Camilo
Baxter, Simon W.
Pardo-Diaz, Carolina
Wu, Grace
Surridge, Alison
Linares, Mauricio
Bermingham, Eldredge
Jiggins, Chris D.
author_sort Salazar, Camilo
collection PubMed
description Homoploid hybrid speciation is the formation of a new hybrid species without change in chromosome number. So far, there has been a lack of direct molecular evidence for hybridization generating novel traits directly involved in animal speciation. Heliconius butterflies exhibit bright aposematic color patterns that also act as cues in assortative mating. Heliconius heurippa has been proposed as a hybrid species, and its color pattern can be recreated by introgression of the H. m. melpomene red band into the genetic background of the yellow banded H. cydno cordula. This hybrid color pattern is also involved in mate choice and leads to reproductive isolation between H. heurippa and its close relatives. Here, we provide molecular evidence for adaptive introgression by sequencing genes across the Heliconius red band locus and comparing them to unlinked wing patterning genes in H. melpomene, H. cydno, and H. heurippa. 670 SNPs distributed among 29 unlinked coding genes (25,847bp) showed H. heurippa was related to H. c. cordula or the three species were intermixed. In contrast, among 344 SNPs distributed among 13 genes in the red band region (18,629bp), most showed H. heurippa related with H. c. cordula, but a block of around 6,5kb located in the 3′ of a putative kinesin gene grouped H. heurippa with H. m. melpomene, supporting the hybrid introgression hypothesis. Genealogical reconstruction showed that this introgression occurred after divergence of the parental species, perhaps around 0.43Mya. Expression of the kinesin gene is spatially restricted to the distal region of the forewing, suggesting a mechanism for pattern regulation. This gene therefore constitutes the first molecular evidence for adaptive introgression during hybrid speciation and is the first clear candidate for a Heliconius wing patterning locus.
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spelling pubmed-28616942010-05-04 Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies Salazar, Camilo Baxter, Simon W. Pardo-Diaz, Carolina Wu, Grace Surridge, Alison Linares, Mauricio Bermingham, Eldredge Jiggins, Chris D. PLoS Genet Research Article Homoploid hybrid speciation is the formation of a new hybrid species without change in chromosome number. So far, there has been a lack of direct molecular evidence for hybridization generating novel traits directly involved in animal speciation. Heliconius butterflies exhibit bright aposematic color patterns that also act as cues in assortative mating. Heliconius heurippa has been proposed as a hybrid species, and its color pattern can be recreated by introgression of the H. m. melpomene red band into the genetic background of the yellow banded H. cydno cordula. This hybrid color pattern is also involved in mate choice and leads to reproductive isolation between H. heurippa and its close relatives. Here, we provide molecular evidence for adaptive introgression by sequencing genes across the Heliconius red band locus and comparing them to unlinked wing patterning genes in H. melpomene, H. cydno, and H. heurippa. 670 SNPs distributed among 29 unlinked coding genes (25,847bp) showed H. heurippa was related to H. c. cordula or the three species were intermixed. In contrast, among 344 SNPs distributed among 13 genes in the red band region (18,629bp), most showed H. heurippa related with H. c. cordula, but a block of around 6,5kb located in the 3′ of a putative kinesin gene grouped H. heurippa with H. m. melpomene, supporting the hybrid introgression hypothesis. Genealogical reconstruction showed that this introgression occurred after divergence of the parental species, perhaps around 0.43Mya. Expression of the kinesin gene is spatially restricted to the distal region of the forewing, suggesting a mechanism for pattern regulation. This gene therefore constitutes the first molecular evidence for adaptive introgression during hybrid speciation and is the first clear candidate for a Heliconius wing patterning locus. Public Library of Science 2010-04-29 /pmc/articles/PMC2861694/ /pubmed/20442862 http://dx.doi.org/10.1371/journal.pgen.1000930 Text en Salazar et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Salazar, Camilo
Baxter, Simon W.
Pardo-Diaz, Carolina
Wu, Grace
Surridge, Alison
Linares, Mauricio
Bermingham, Eldredge
Jiggins, Chris D.
Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title_full Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title_fullStr Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title_full_unstemmed Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title_short Genetic Evidence for Hybrid Trait Speciation in Heliconius Butterflies
title_sort genetic evidence for hybrid trait speciation in heliconius butterflies
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861694/
https://www.ncbi.nlm.nih.gov/pubmed/20442862
http://dx.doi.org/10.1371/journal.pgen.1000930
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