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Helicobacter pylori VacA Toxin/Subunit p34: Targeting of an Anion Channel to the Inner Mitochondrial Membrane
The vacuolating toxin VacA, released by Helicobacter pylori, is an important virulence factor in the pathogenesis of gastritis and gastroduodenal ulcers. VacA contains two subunits: The p58 subunit mediates entry into target cells, and the p34 subunit mediates targeting to mitochondria and is essent...
Autores principales: | Domańska, Grażyna, Motz, Christian, Meinecke, Michael, Harsman, Anke, Papatheodorou, Panagiotis, Reljic, Boris, Dian-Lothrop, Elke A., Galmiche, Antoine, Kepp, Oliver, Becker, Lars, Günnewig, Kathrin, Wagner, Richard, Rassow, Joachim |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861713/ https://www.ncbi.nlm.nih.gov/pubmed/20442789 http://dx.doi.org/10.1371/journal.ppat.1000878 |
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