Genome-wide association study of intracranial aneurysm identifies three new risk loci

Saccular intracranial aneurysms (IAs) are balloon-like dilations of the intracranial arterial wall; their hemorrhage commonly results in severe neurologic impairment and death. We report a second genome-wide association study with discovery and replication cohorts from Europe and Japan comprising 5,...

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Autores principales: Yasuno, Katsuhito, Bilguvar, Kaya, Bijlenga, Philippe, Low, Siew Kee, Krischek, Boris, Auburger, Georg, Simon, Matthias, Krex, Dietmar, Arlier, Zulfikar, Nayak, Nikhil, Ruigrok, Ynte M, Niemela, Mika, Tajima, Atsushi, von und zu Fraunberg, Mikael, Doczi, Tamas, Wirjatijasa, Florentina, Hata, Akira, Blasco, Jordi, Oszvald, Agi, Kasuya, Hidetoshi, Zilani, Gulam, Schoch, Beate, Singh, Pankaj, Stüer, Carsten, Risselada, Roelof, Beck, Jürgen, Sola, Teresa, Ricciardi, Filomena, Aromaa, Arpo, Illig, Thomas, Schreiber, Stefan, van Duijn, Cornelia M, van den Berg, Leonard H, Perret, Claire, Proust, Carole, Roder, Constantin, Ozturk, Ali K, Gaál, Emília, Berg, Daniela, Geisen, Christof, Friedrich, Christoph M, Summers, Paul, Frangi, Alejandro F, State, Matthew W, Wichmann, HErich, Breteler, Monique M B, Wijmenga, Cisca, Mane, Shrikant, Peltonen, Leena, Elio, Vivas, Sturkenboom, Miriam CJM, Lawford, Patricia, Byrne, James, Macho, Juan, Sandalcioglu, Erol I, Meyer, Bernhard, Raabe, Andreas, Steinmetz, Helmuth, Rüfenacht, Daniel, Jääskeläinen, Juha E, Hernesniemi, Juha, Rinkel, Gabriel J E, Zembutsu, Hitoshi, Inoue, Ituro, Palotie, Aarno, Cambien, François, Nakamura, Yusuke, Lifton, Richard P, Günel, Murat
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861730/
https://www.ncbi.nlm.nih.gov/pubmed/20364137
http://dx.doi.org/10.1038/ng.563

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