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IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses

CD4(pos) T helper (Th) 2 cells secrete interleukin (IL)-4, IL-5 and IL-13 and are required for immunity to gastrointestinal helminth infections1. However, Th2 cells also promote chronic inflammation associated with asthma and allergic disorders2. The non-hematopoietic cell-derived cytokines thymic s...

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Detalles Bibliográficos
Autores principales: Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861732/
https://www.ncbi.nlm.nih.gov/pubmed/20200520
http://dx.doi.org/10.1038/nature08901