Cargando…

IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses

CD4(pos) T helper (Th) 2 cells secrete interleukin (IL)-4, IL-5 and IL-13 and are required for immunity to gastrointestinal helminth infections1. However, Th2 cells also promote chronic inflammation associated with asthma and allergic disorders2. The non-hematopoietic cell-derived cytokines thymic s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saenz, Steven A., Siracusa, Mark C., Perrigoue, Jacqueline G., Spencer, Sean P., Urban, Joseph F., Tocker, Joel E., Budelsky, Alison L., Kleinschek, Melanie A., Kastelein, Robert A., Kambayashi, Taku, Bhandoola, Avinash, Artis, David
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861732/ https://www.ncbi.nlm.nih.gov/pubmed/20200520 http://dx.doi.org/10.1038/nature08901

Ejemplares similares

IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPP(type2)) cells
por: Saenz, Steven A., et al.
Publicado: (2013)

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine
por: Zaph, Colby, et al.
Publicado: (2008)

Development and differentiation of early innate lymphoid progenitors
por: Harly, Christelle, et al.
Publicado: (2018)

Major histocompatibility complex class II-dependent basophil-CD4(+) T cell interactions promote T(H)2 cytokine-dependent immunity
por: Perrigoue, Jacqueline G., et al.
Publicado: (2009)

Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
por: Owyang, Alexander M., et al.
Publicado: (2006)

Potent antibody lineage against malaria transmission elicited by human vaccination with Pfs25
por: McLeod, Brandon, et al.
Publicado: (2019)

IL-25 induces type 2 cytokine production in a novel, steroid resistant IL-17RB(+) myeloid population that exacerbates asthmatic pathology
por: Petersen, Bryan C., et al.
Publicado: (2012)

Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity
por: Agarwal, Yash, et al.
Publicado: (2022)

Obesity Exacerbates the Cytokine Storm Elicited by Francisella tularensis Infection of Females and Is Associated with Increased Mortality
por: Ramos Muniz, Mireya G., et al.
Publicado: (2018)

In Vitro Evidence That Cytokine Receptor Signals Are Required for Differentiation of Double Positive Thymocytes into Functionally Mature CD8(+) T Cells
por: Yu, Qing, et al.
Publicado: (2003)

The Earliest Step in B Lineage Differentiation from Common Lymphoid Progenitors Is Critically Dependent upon Interleukin 7
por: Miller, Juli P., et al.
Publicado: (2002)

Early TRAIL-engagement elicits potent multimodal targeting of melanoma by CD34(+) progenitor cell-derived NK cells
por: van Vliet, Amanda A., et al.
Publicado: (2023)

IL-25 regulates Th17 function in autoimmune inflammation
por: Kleinschek, Melanie A., et al.
Publicado: (2007)

Switch hitter: Bcl11b in T cells and ILC2s
por: Harly, Christelle, et al.
Publicado: (2019)

Commensal bacterial–derived signals regulate basophil hematopoiesis and allergic inflammation
por: Hill, David A., et al.
Publicado: (2012)

PRMT5 Is Required for T Cell Survival and Proliferation by Maintaining Cytokine Signaling
por: Tanaka, Yukinori, et al.
Publicado: (2020)

The prostaglandin D(2) receptor CRTH2 regulates accumulation of group 2 innate lymphoid cells in the inflamed lung
por: Tait Wojno, ED, et al.
Publicado: (2015)

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow
por: Yang, Qi, et al.
Publicado: (2015)

Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets
por: Ghaedi, Maryam, et al.
Publicado: (2019)

Lymphangiogenesis-inducing vaccines elicit potent and long-lasting T cell immunity against melanomas
por: Sasso, Maria Stella, et al.
Publicado: (2021)

Potent and broad neutralization of HIV-1 by a llama antibody elicited by immunization
por: McCoy, Laura E., et al.
Publicado: (2012)

Multiplexed activation of endogenous genes by CRISPRa elicits potent anti-tumor immunity
por: Wang, Guangchuan, et al.
Publicado: (2019)

Delta breakthrough infections elicit potent, broad and durable neutralizing antibody responses
por: Walls, Alexandra C., et al.
Publicado: (2021)

BCG Vaccination in Humans Elicits Trained Immunity via the Hematopoietic Progenitor Compartment
por: Cirovic, Branko, et al.
Publicado: (2020)

Postnatal Involution and Counter-Involution of the Thymus
por: Cowan, Jennifer E., et al.
Publicado: (2020)

Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes
por: Li, Leike, et al.
Publicado: (2019)

Blocked O-GlcNAc cycling disrupts mouse hematopoeitic stem cell maintenance and early T cell development
por: Abramowitz, Lara K., et al.
Publicado: (2019)

Algae-Produced Pfs25 Elicits Antibodies That Inhibit Malaria Transmission
por: Gregory, James A., et al.
Publicado: (2012)

Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23
por: Donaldson, D S, et al.
Publicado: (2015)

Cycloguanil and Analogues Potently Target DHFR in Cancer Cells to Elicit Anti-Cancer Activity
por: Brown, Jennifer I., et al.
Publicado: (2023)

Immature Thymocytes Undergoing Receptor Rearrangements Are Resistant to an Atm-Dependent Death Pathway Activated in Mature T Cells by Double-Stranded DNA Breaks
por: Bhandoola, Avinash, et al.
Publicado: (2000)

IL-31–IL-31R interactions negatively regulate type 2 inflammation in the lung
por: Perrigoue, Jacqueline G., et al.
Publicado: (2007)

Heterologous booster COVID-19 vaccination elicited potent immune responses in HCWs
por: Saltoğlu, Neşe, et al.
Publicado: (2022)

Single-injection COVID-19 subunit vaccine elicits potent immune responses
por: Zhou, Xiaoyong, et al.
Publicado: (2022)

Cytokines Induce Faster Membrane Diffusion of MHC Class I and the Ly49A Receptor in a Subpopulation of Natural Killer Cells
por: Bagawath-Singh, Sunitha, et al.
Publicado: (2016)

Optimization of Elicitation Conditions to Enhance the Production of Potent Metabolite Withanolide from Withania somnifera (L.)
por: Singh, Manali, et al.
Publicado: (2022)

Polyvalent mRNA vaccination elicited potent immune response to monkeypox virus surface antigens
por: Fang, Zhenhao, et al.
Publicado: (2023)

Isotype Switching Converts Anti-CD40 Antagonism to Agonism to Elicit Potent Antitumor Activity
por: Yu, Xiaojie, et al.
Publicado: (2020)

CD25 expression could be a prognostic marker of bexarotene monotherapy for cutaneous T‐cell lymphomas
por: Yamamoto, Jun, et al.
Publicado: (2023)

Oncolytic Immunotherapy: Dying the Right Way is a Key to Eliciting Potent Antitumor Immunity
por: Guo, Zong Sheng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_5f1sinu1pb76jf02fkos7ntsdp