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Diagnostic dilemma in a child with congenital heart disease on sildenafil

Sildenafil is used in infants and children mainly for the treatment of pulmonary hypertension associated with congenital heart disease. Some side-effects of sildenafil are similar to the symptoms and signs of congestive heart failure in children. We present a case of a two-month-old infant with supr...

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Detalles Bibliográficos
Autores principales: Zaki, Syed Ahmed, Dadge, Deepak, Asif, Shujaath, Shanbag, Preeti
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2861818/
https://www.ncbi.nlm.nih.gov/pubmed/20442825
http://dx.doi.org/10.4103/0253-7613.55203
Descripción
Sumario:Sildenafil is used in infants and children mainly for the treatment of pulmonary hypertension associated with congenital heart disease. Some side-effects of sildenafil are similar to the symptoms and signs of congestive heart failure in children. We present a case of a two-month-old infant with supracardiac total anomalous venous connection and pulmonary hypertension, who presented with severe sweating and tachycardia after institution of sildenafil therapy. He improved dramatically on discontinuation of the drug.