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Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancer
BACKGROUND: The secreted protein acidic and rich in cysteine (SPARC) plays a pivotal role in regulating cell-matrix interactions and tumor angiogenesis, proliferation, and migration. Detection of SPARC gene methylation may be useful as a tumorigenesis marker for early detection of pancreatic cancer....
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862018/ https://www.ncbi.nlm.nih.gov/pubmed/20338068 http://dx.doi.org/10.1186/1756-9966-29-28 |