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Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancer

BACKGROUND: The secreted protein acidic and rich in cysteine (SPARC) plays a pivotal role in regulating cell-matrix interactions and tumor angiogenesis, proliferation, and migration. Detection of SPARC gene methylation may be useful as a tumorigenesis marker for early detection of pancreatic cancer....

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Detalles Bibliográficos
Autores principales:	Gao, Jun, Song, Jian, Huang, Haojie, Li, Zhaoshen, Du, Yiqi, Cao, Jia, Li, Minghui, Lv, Shunli, Lin, Han, Gong, Yanfang
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862018/ https://www.ncbi.nlm.nih.gov/pubmed/20338068 http://dx.doi.org/10.1186/1756-9966-29-28

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