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Conditional Gene Expression and RNAi Using MEC-8-Dependent Splicing in C. elegans

We describe a method for conditional regulation of gene expression based on the processing of an intron cassette by a splicing factor. The RNA processing factor MEC-8 is necessary for the function of the Caenorhabditis elegans touch receptor neurons; mec-8 mutants are touch insensitive. We show here...

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Detalles Bibliográficos
Autores principales:	Calixto, Andrea, Ma, Charles, Chalfie, Martin
Formato:	Texto
Lenguaje:	English
Publicado:	2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862115/ https://www.ncbi.nlm.nih.gov/pubmed/20364149 http://dx.doi.org/10.1038/nmeth.1445

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