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The membrane attack complex of complement drives the progression of atherosclerosis in apolipoprotein E knockout mice

AIMS: To examine the roles of the membrane attack complex of complement and its sole membrane regulator, CD59, in atherosclerosis. METHODS: C6 (C6(−/−)) deficient and CD59a (Cd59a(−/−)) knockout mice were separately crossed onto the apolipoprotein E knockout (apoE(−/−)) background. The double knocko...

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Detalles Bibliográficos
Autores principales:	Lewis, Ruth D., Jackson, Christopher L., Morgan, B. Paul, Hughes, Timothy R.
Formato:	Texto
Lenguaje:	English
Publicado:	Pergamon Press 2010
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862291/ https://www.ncbi.nlm.nih.gov/pubmed/19959238 http://dx.doi.org/10.1016/j.molimm.2009.10.035

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