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Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman wit...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Hindawi Publishing Corporation
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862322/ https://www.ncbi.nlm.nih.gov/pubmed/20454648 http://dx.doi.org/10.1155/2010/812424 |
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author | Kim, Stefano C. H. Natarajan-Ame, Shanti Lioure, Bruno Chenard, Marie-Pierre Duclos, Brigitte Herbrecht, Raoul Bergerat, Jean-Pierre |
author_facet | Kim, Stefano C. H. Natarajan-Ame, Shanti Lioure, Bruno Chenard, Marie-Pierre Duclos, Brigitte Herbrecht, Raoul Bergerat, Jean-Pierre |
author_sort | Kim, Stefano C. H. |
collection | PubMed |
description | Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman with vaginal bleeding and a large cervical mass. Further evaluation confirmed the presence of a granulocytic sarcoma but failed to reveal systemic involvement. Results. AML type chemotherapy followed by radiotherapy of the uterus led to a durable complete remission. She remains in complete remission six years after diagnosis. Conclusion. Granulocytic sarcoma of the cervix is a rare entity for which early intensive AML type therapy is effective. |
format | Text |
id | pubmed-2862322 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2010 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-28623222010-05-07 Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up Kim, Stefano C. H. Natarajan-Ame, Shanti Lioure, Bruno Chenard, Marie-Pierre Duclos, Brigitte Herbrecht, Raoul Bergerat, Jean-Pierre J Oncol Case Report Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman with vaginal bleeding and a large cervical mass. Further evaluation confirmed the presence of a granulocytic sarcoma but failed to reveal systemic involvement. Results. AML type chemotherapy followed by radiotherapy of the uterus led to a durable complete remission. She remains in complete remission six years after diagnosis. Conclusion. Granulocytic sarcoma of the cervix is a rare entity for which early intensive AML type therapy is effective. Hindawi Publishing Corporation 2010 2010-04-29 /pmc/articles/PMC2862322/ /pubmed/20454648 http://dx.doi.org/10.1155/2010/812424 Text en Copyright © 2010 Stefano C. H. Kim et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Kim, Stefano C. H. Natarajan-Ame, Shanti Lioure, Bruno Chenard, Marie-Pierre Duclos, Brigitte Herbrecht, Raoul Bergerat, Jean-Pierre Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title | Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title_full | Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title_fullStr | Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title_full_unstemmed | Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title_short | Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up |
title_sort | successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862322/ https://www.ncbi.nlm.nih.gov/pubmed/20454648 http://dx.doi.org/10.1155/2010/812424 |
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