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Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up

Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman wit...

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Autores principales: Kim, Stefano C. H., Natarajan-Ame, Shanti, Lioure, Bruno, Chenard, Marie-Pierre, Duclos, Brigitte, Herbrecht, Raoul, Bergerat, Jean-Pierre
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862322/
https://www.ncbi.nlm.nih.gov/pubmed/20454648
http://dx.doi.org/10.1155/2010/812424
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author Kim, Stefano C. H.
Natarajan-Ame, Shanti
Lioure, Bruno
Chenard, Marie-Pierre
Duclos, Brigitte
Herbrecht, Raoul
Bergerat, Jean-Pierre
author_facet Kim, Stefano C. H.
Natarajan-Ame, Shanti
Lioure, Bruno
Chenard, Marie-Pierre
Duclos, Brigitte
Herbrecht, Raoul
Bergerat, Jean-Pierre
author_sort Kim, Stefano C. H.
collection PubMed
description Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman with vaginal bleeding and a large cervical mass. Further evaluation confirmed the presence of a granulocytic sarcoma but failed to reveal systemic involvement. Results. AML type chemotherapy followed by radiotherapy of the uterus led to a durable complete remission. She remains in complete remission six years after diagnosis. Conclusion. Granulocytic sarcoma of the cervix is a rare entity for which early intensive AML type therapy is effective.
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spelling pubmed-28623222010-05-07 Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up Kim, Stefano C. H. Natarajan-Ame, Shanti Lioure, Bruno Chenard, Marie-Pierre Duclos, Brigitte Herbrecht, Raoul Bergerat, Jean-Pierre J Oncol Case Report Background. Localized granulocytic sarcoma of the uterine cervix in the absence of acute myelogenous leukemia (AML) at presentation is very rare, its diagnosis is often delayed, and its prognosis almost always ominous evolving into refractory AML. Case. We present the case of a 30-year-old woman with vaginal bleeding and a large cervical mass. Further evaluation confirmed the presence of a granulocytic sarcoma but failed to reveal systemic involvement. Results. AML type chemotherapy followed by radiotherapy of the uterus led to a durable complete remission. She remains in complete remission six years after diagnosis. Conclusion. Granulocytic sarcoma of the cervix is a rare entity for which early intensive AML type therapy is effective. Hindawi Publishing Corporation 2010 2010-04-29 /pmc/articles/PMC2862322/ /pubmed/20454648 http://dx.doi.org/10.1155/2010/812424 Text en Copyright © 2010 Stefano C. H. Kim et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kim, Stefano C. H.
Natarajan-Ame, Shanti
Lioure, Bruno
Chenard, Marie-Pierre
Duclos, Brigitte
Herbrecht, Raoul
Bergerat, Jean-Pierre
Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title_full Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title_fullStr Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title_full_unstemmed Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title_short Successful Treatment of a Granulocytic Sarcoma of the Uterine Cervix in Complete Remission at Six-Year Follow-Up
title_sort successful treatment of a granulocytic sarcoma of the uterine cervix in complete remission at six-year follow-up
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862322/
https://www.ncbi.nlm.nih.gov/pubmed/20454648
http://dx.doi.org/10.1155/2010/812424
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