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Phase I and Pharmacokinetic Study of ABI-007, Albumin-bound Paclitaxel, Administered Every 3 Weeks in Japanese Patients with Solid Tumors
OBJECTIVE: ABI-007 is a novel Cremophor(®) EL-free nanoparticle albumin-bound paclitaxel. This Phase I study was designed to evaluate tolerability and determine recommended dose for Japanese patients when ABI-007 was administered in every-3-week schedule. Pharmacokinetics of paclitaxel was also asse...
Autores principales: | Yamada, Kazuhiko, Yamamoto, Noboru, Yamada, Yasuhide, Mukohara, Toru, Minami, Hironobu, Tamura, Tomohide |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862657/ https://www.ncbi.nlm.nih.gov/pubmed/20133335 http://dx.doi.org/10.1093/jjco/hyp192 |
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