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Proteomic Profiling of Human Keratinocytes Undergoing UVB-Induced Alternative Differentiation Reveals TRIpartite Motif Protein 29 as a Survival Factor

BACKGROUND: Repeated exposures to UVB of human keratinocytes lacking functional p16(INK-4a) and able to differentiate induce an alternative state of differentiation rather than stress-induced premature senescence. METHODOLOGY/PRINCIPAL FINDINGS: A 2D-DIGE proteomic profiling of this alternative stat...

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Detalles Bibliográficos
Autores principales: Bertrand-Vallery, Véronique, Belot, Nathalie, Dieu, Marc, Delaive, Edouard, Ninane, Noëlle, Demazy, Catherine, Raes, Martine, Salmon, Michel, Poumay, Yves, Debacq-Chainiaux, Florence, Toussaint, Olivier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862717/
https://www.ncbi.nlm.nih.gov/pubmed/20454669
http://dx.doi.org/10.1371/journal.pone.0010462