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Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy

In the radiotherapy treatment planning of a lesion located in the head region with small field radiation beams, the heterogeneity corrections play an important role. In this work, we investigated the influence of a bony heterogeneity on dose profile inside a soft tissue phantom containing a bony mat...

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Detalles Bibliográficos
Autores principales: Cardoso, Simone C., Alves, Victor Gabriel L., da Rosa, Luiz Antonio R., Campos, Luciana T., Batista, Delano V. S., Facure, Alessandro
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862736/
https://www.ncbi.nlm.nih.gov/pubmed/20454675
http://dx.doi.org/10.1371/journal.pone.0010466
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author Cardoso, Simone C.
Alves, Victor Gabriel L.
da Rosa, Luiz Antonio R.
Campos, Luciana T.
Batista, Delano V. S.
Facure, Alessandro
author_facet Cardoso, Simone C.
Alves, Victor Gabriel L.
da Rosa, Luiz Antonio R.
Campos, Luciana T.
Batista, Delano V. S.
Facure, Alessandro
author_sort Cardoso, Simone C.
collection PubMed
description In the radiotherapy treatment planning of a lesion located in the head region with small field radiation beams, the heterogeneity corrections play an important role. In this work, we investigated the influence of a bony heterogeneity on dose profile inside a soft tissue phantom containing a bony material. PDD curves were obtained by simulation using the Monte Carlo code EGSnrc and employing Eclipse® treatment planning system algorithms (Batho, Modified Batho, Equivalent TAR and Anisotropic Analytic Algorithm) for a 15 MV photon beam and field sizes of 2×2 and 10×10 cm(2). The Equivalent TAR method exhibited better agreement with Monte Carlo simulations for the 2×2 cm(2) field size. The magnitude of the effect on PDD due to the bony heterogeneity for 1×1, 2×2 and 10×10 cm(2) field sizes increases to 10, 5 and 3%, respectively.
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spelling pubmed-28627362010-05-07 Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy Cardoso, Simone C. Alves, Victor Gabriel L. da Rosa, Luiz Antonio R. Campos, Luciana T. Batista, Delano V. S. Facure, Alessandro PLoS One Research Article In the radiotherapy treatment planning of a lesion located in the head region with small field radiation beams, the heterogeneity corrections play an important role. In this work, we investigated the influence of a bony heterogeneity on dose profile inside a soft tissue phantom containing a bony material. PDD curves were obtained by simulation using the Monte Carlo code EGSnrc and employing Eclipse® treatment planning system algorithms (Batho, Modified Batho, Equivalent TAR and Anisotropic Analytic Algorithm) for a 15 MV photon beam and field sizes of 2×2 and 10×10 cm(2). The Equivalent TAR method exhibited better agreement with Monte Carlo simulations for the 2×2 cm(2) field size. The magnitude of the effect on PDD due to the bony heterogeneity for 1×1, 2×2 and 10×10 cm(2) field sizes increases to 10, 5 and 3%, respectively. Public Library of Science 2010-05-03 /pmc/articles/PMC2862736/ /pubmed/20454675 http://dx.doi.org/10.1371/journal.pone.0010466 Text en Cardoso et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Cardoso, Simone C.
Alves, Victor Gabriel L.
da Rosa, Luiz Antonio R.
Campos, Luciana T.
Batista, Delano V. S.
Facure, Alessandro
Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title_full Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title_fullStr Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title_full_unstemmed Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title_short Monte Carlo Simulation of Bony Heterogeneity Effects on Dose Profile for Small Irradiation Field in Radiotherapy
title_sort monte carlo simulation of bony heterogeneity effects on dose profile for small irradiation field in radiotherapy
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862736/
https://www.ncbi.nlm.nih.gov/pubmed/20454675
http://dx.doi.org/10.1371/journal.pone.0010466
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