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Genetic Interactions Show the Importance of rRNA Modification Machinery for the Role of Rps15p during Ribosome Biogenesis in S. cerevisiæ

Rps15p, an essential ribosomal protein, was previously shown to be critical for nuclear export of small subunit pre-particles. We have designed a synthetic lethal screen in Saccharomyces cerevisiæ to identify its genetic partners and further elucidate its role during ribosomal biogenesis. Our screen...

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Detalles Bibliográficos
Autores principales: Bellemer, Clément, Chabosseau, Pauline, Gallardo, Franck, Gleizes, Pierre-Emmanuel, Stahl, Guillaume
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2862742/
https://www.ncbi.nlm.nih.gov/pubmed/20454621
http://dx.doi.org/10.1371/journal.pone.0010472