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Heparan Sulfate Chain Valency Controls Syndecan-4 Function in Cell Adhesion
Fibroblasts null for the transmembrane proteoglycan, syndecan-4, have an altered actin cytoskeleton, compared with matching wild-type cells. They do not organize α-smooth muscle actin into bundles, but will do so when full-length syndecan-4 is re-expressed. This requires the central V region of the...
Autores principales: | Gopal, Sandeep, Bober, Adam, Whiteford, James R., Multhaupt, Hinke A. B., Yoneda, Atsuko, Couchman, John R. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2863221/ https://www.ncbi.nlm.nih.gov/pubmed/20154082 http://dx.doi.org/10.1074/jbc.M109.056945 |
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