Mouse Rad1 deletion enhances susceptibility for skin tumor development

BACKGROUND: Cells are constantly exposed to stresses from cellular metabolites as well as environmental genotoxins. DNA damage caused by these genotoxins can be efficiently fixed by DNA repair in cooperation with cell cycle checkpoints. Unrepaired DNA lesions can lead to cell death, gene mutation an...

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Detalles Bibliográficos
Autores principales: Han, Lu, Hu, Zhishang, Liu, Yuheng, Wang, Xiangyuan, Hopkins, Kevin M, Lieberman, Howard B, Hang, Haiying
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864214/
https://www.ncbi.nlm.nih.gov/pubmed/20334655
http://dx.doi.org/10.1186/1476-4598-9-67

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864214/
https://www.ncbi.nlm.nih.gov/pubmed/20334655
http://dx.doi.org/10.1186/1476-4598-9-67

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