MicroRNA-184 inhibits neuroblastoma cell survival through targeting the serine/threonine kinase AKT2

BACKGROUND: Neuroblastoma is a paediatric cancer of the sympathetic nervous system. The single most important genetic indicator of poor clinical outcome is amplification of the MYCN transcription factor. One of many down-stream MYCN targets is miR-184, which is either directly or indirectly represse...

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Detalles Bibliográficos
Autores principales: Foley, Niamh H, Bray, Isabella M, Tivnan, Amanda, Bryan, Kenneth, Murphy, Derek M, Buckley, Patrick G, Ryan, Jacqueline, O'Meara, Anne, O'Sullivan, Maureen, Stallings, Raymond L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864218/
https://www.ncbi.nlm.nih.gov/pubmed/20409325
http://dx.doi.org/10.1186/1476-4598-9-83

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