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GPR30, but not estrogen receptor-α, is crucial in the treatment of experimental autoimmune encephalomyelitis by oral ethinyl estradiol
BACKGROUND: Remission of multiple sclerosis during periods of high ovarian hormone secretion (such as pregnancy) has led to a great deal of interest in the potential for estrogens to treat autoimmune disease. Previous work has established that 17β-estradiol can inhibit onset of experimental autoimmu...
Autores principales: | Yates, Melissa A, Li, Yuexin, Chlebeck, Peter J, Offner, Halina |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864220/ https://www.ncbi.nlm.nih.gov/pubmed/20403194 http://dx.doi.org/10.1186/1471-2172-11-20 |
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