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Specificity and functionality of microRNA inhibitors
BACKGROUND: Micro(mi)RNAs regulate gene expression through translational attenuation and messenger (m)RNA degradation, and are associated with differentiation, homeostasis and disease. Natural miRNA target recognition is determined primarily by perfect complementarity in a seed region (nucleotide po...
Autores principales: | Robertson, Barbara, Dalby, Andrew B, Karpilow, Jon, Khvorova, Anastasia, Leake, Devin, Vermeulen, Annaleen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864222/ https://www.ncbi.nlm.nih.gov/pubmed/20359337 http://dx.doi.org/10.1186/1758-907X-1-10 |
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